Fenbendazole has been a well-known antiparasitic agent used in animals for years. It is effective against many species of intestinal parasites, including roundworms and tapeworms. However, in recent years, it has increasingly been used for applications beyond its traditional veterinary use. It all began with the story of Joe Tippens, an American who announced on social media that he used fenbendazole, among other substances, to combat cancer.
How does it work?
Fenbendazole binds to tubulins – the labyrinthine membranes of microtubules responsible for cell division. In cancer cells, this disrupts the normal process of mitosis, which can lead to their death. Furthermore, fenbendazole affects cellular metabolism, causing oxidative stress and energy disruption in cancer cells.
What does the science say?
Although there are no large-scale human clinical trials, numerous in vitro and animal studies suggest that fenbendazole may inhibit the growth of certain types of cancer, including lung, prostate, and colon cancer. It is also well-tolerated, making it an interesting candidate for further study.